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Celebrating 70 Years
 Over 130 friends and alumni of Duke Dermatology gathered on October 19 – 21,
2007 to celebrate our 70th anniversary of Dr. Cal’s starting Duke Dermatology and to celebrate the outstanding
career of Dr. Sheldon Pinnell, J. Lamar Callaway Professor of Dermatology, Emeritus.
On July 1, 1937 Dr. J. Lamar Callaway returned to Duke University School of Medicine to become the head of Dermatology.
Dr. Cal was 26 years old and remained head of the Division of Dermatology until
1975. July 1, 2007 is the 70th anniversary of Duke Dermatology.
Why Choose a Duke Residency?
The close integration of clinical and basic science activities provides a solid
foundation in the fundamentals of dermatologic pathophysiology as they are applied
to patient care.
The goal of the residency program in Dermatology at Duke University Medical Center
is to train physicians to become excellent clinical dermatologists and leaders
in academic and clinical dermatology.
Faculty & Resident in the News
 Dr. Elise Olsen is heading a new national initiative in cutaneous lymphoma. Dr. Olsen is a founder
and, as of March 2009, was elected President of the United States Consortium for
Cutaneous Lymphomas (USCCL). This Society has 4 main objectives--to start a national
registry and tissue bank, to extend education of physicians taking care of patients
with cutaneous lymphoma, and to establish an active Clinical Trials Network to
do collaborative clinical trials. The USCCL is unique also in that it is a multidisciplinary group of dermatologists, oncologists,
dermatopathologists and radiation oncologists working under the assumption that
communication and collaboration provides the best milieu for investigative study
and advancement in patient care. The registry will be housed at the Duke Clinical
Research Institute. Dr. Madeleine Duvic (Duke Dermatology 1980) is also involved in the Society and will Chair the Trials
Network.
 Dr. Kelly Nelson was recently interviewed on NBC Nightly News regarding her studies utilizing the new technology of real time confocal microscopy
for the diagnosis of skin cancers. This technology holds the promise of offering
early diagnosis of skin cancers including malignant melanoma, without the use
of an invasive skin biopsy. Studies are underway to determine how this new technique
can be used to benefit patients with earlier diagnosis and treatment of skin cancers
Duke Dermatology was active at the recent national meeting of the Society for Investigative Dermatology held May 6 - 9 in Montreal, Canada.
Dr. Jennifer Zhang's lab presented work on the molecular mechanisms that control the development of skin cancer. (link to abstracts) In addition, Dr. Zhang chaired the session on Growth Factors and Signal Transduction. Dr. Robert Walters presented his work on the molecular mechanisms of the facial flushing associated with the use of
niacin, an important drug used to treat elevated blood lipids. Dr. Heather Yeowell presented her work on the mechanisms of increased lysyl hydroxylase 2 long form that is found in
scleroderma, which may suggest new therapies for scleroderma. Dr. Russell Hall presented his work on the use of new anti-B cell therapies for the treatment of bullous pemphigoid
and for the changes in B cells that occur with this treatment.
Dr. Robert Walters has reported in the Journal of Clinical Investigation on his findings that the facial flushing which occurs with ingestion of the
drug Niacin is mediated by beta arrestin 1 signaling. The advantageous lipid lowering
effect of the drug is not mediated via this mechanism. News 14 picked up the story
Dr. Robert Walters was awarded a Dermatology Foundation Physician Scientist Career Development Award (complete list of award recipients) for his work on Beta Arrestin mediated signaling.
Dr. Puneet Seth, Ph.D, a Research Associate in Duke Dermatology, has recently
been awarded a Postdoctoral Travel Fellowship by the American Society for Biochemistry
and Molecular Biology (ASBMB).
Dr. Seth was awarded this prestigious Travel Fellowship to present his latest
data in scleroderma research carried out in Dr. Heather Yeowell's research laboratory. This
work is funded by the National Institute of Aging and Scleroderma Foundation Grants
to Prof. Yeowell (Principal Investigator) and will be presented at the ASBMB Annual Meeting in New Orleans , LA in April 2009.
 Dr. Jennifer Zhang , PhD, received an award from the Skin Cancer Foundation for a project testing the feasibility of targeting c-Jun and c-Fos for skin cancer
treatment.
First Annual Fred Blum (HS 1986-1989) Lectureship delivered by Dr. Lisa Beck
(HS 1987-1990)
Duke Dermatology lost a great friend with the death of Dr. Fred Blum on October
17, 2008. Fred completed his residency in Dermatology at Duke in 1989 and practiced
dermatology in Durham, most recently with Duke Dermatology graduates Drs. Lori
Etter, Craig Heinly and Steve Higgins. Fred was committed to teaching and learning
about dermatology. He was an active volunteer teacher at the Durham VA Medical
Center and recruited other outstanding dermatologist to participate in our teaching
program at the VA. Fred was also an enthusiastic participant in our monthly Duke
UNC Clinical Conferences, asking probing questions and relishing the camaraderie
that is so typical of dermatology in our community.
 In honor of Fred and his commitment to learning and dermatology we have established
the Fred Blum Lectureship in Dermatology at Duke. We were honored to have as
our first Blum Lecturer a residency class mate of Fred’s, Dr. Lisa Beck, Associate
Professor of Dermatology, University of Rochester. Dr. Beck is a world expert
in dermatologic allergy including urticaria and atopy. Her lecture with practical
tips and the latest scientific advances was typical of what excited Fred about
the never ending enjoyment in learning dermatology. We are raising funds to support
this lectureship in perpetuity so that all future Duke residents and community
dermatologists will remember the enthusiasm, the joy of learning and the commitment
to outstanding patient care that marked Fred’s career in dermatology. Contributions
to the Fred Blum Lectureship in Dermatology can be made by sending your tax deductible
contributions to Duke Dermatology, Box 3135, Duke University Medical Center Durham,
NC, 27710.
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News/Links
Welcome to the Department of Dermatology at Duke University Medical Center. Duke
Dermatology has a long tradition that began when Dr. J. Lamar Callaway founded
the Division in 1939.
Dr. Russell P Hall, III
J. Lamar Callaway Professor and Chair
Duke Dermatology: Teaching, Investigating and Caring.
Reflections from the Chair
New Faculty
Priya Venkatesan, MD
(July 2009)
Jane Bellet, MD
(February 2009)
Caroline Rao, MD.,
(September 2008)
Amber Atwater, MD.,
(August 2008)
Links of Interest:
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Recent Publications
2. A topical antioxidant solution containing vitamins C and E stabilized by ferulic
acid provides protection for human skin against damage caused by ultraviolet irradiation. Murray JC, Burch JA, Streilein RD, Iannacchione MA, Hall RP, Pinnell SR. J Am Acad Dermatol. 2008 Sep;59(3):418-25. Epub 2008 Jul 7.
3. Olsen EA, Kim YH, Kuzel TM, Pacheco TR, Foss FM et al.: A Phase IIb multicenter trial
of Vorinostat (Suberoylanilide Hydroxamic Acid, SAHA) in patients with persistent,
progressive or treatment refractory mycosis fungoides or Sézary Syndrome subtypes
of cutaneous T-cell lymphoma. J Clin Oncol; 25(21): 3109-3115, 2007.
4. Olsen EA, Vonderheid E, Pimpinelli N, Willemze R, Kim Y, et al.: Revisions to the staging
and classification of mycosis fungoides and Sezary Syndrome: a proposal of the
International Society for Cutaneous Lymphomas (ISCL) and the Cutaneous Lymphoma
Study Group of the European Organization of Research and Treatment of Cancer (EORTC).
Blood; 110(6): 1708-1709, 2007.
5. Zhang JY, Adams AE, Ridky TW, Tao S, Khavari PA. Tumor necrosis factor receptor 1/c-Jun-NH2-Kinase signaling promotes human neoplasia.
Cancer Research 67: 3827-34, 2007.
6. Hall RP, Benbenisty KM, Mickle C, Takeuchi F, Streilein, RD. Serum IL-8 in patients
with dermatitis herpetiformis (DH) is produced in response to dietary gluten.
J Invest Dermatol 127:2158-65,2007
7. Stryjewski ME, Hall RP, Chu VH, Kanafani ZA, O’Rioran WD, Weinstock M, Stienecker RS, Streilein RD,
Dorschner RA, Fowler Jr VG, Corey GR, Gallo RL. Expression of antimicrobial peptides
in normal and infected skin of patients with infective cellulitis. J Infect Dis 196:1425-30, 2007.
8. Berkowitz P, Diaz L.A., Hall RP, Rubenstein DS. Induction of p38MAPK and HSP27 phosphorylation in pemphigus
vulgaris patient skin. J Invest Dermatol 128: 738-740, 2007.
9. Adler AS, Sinha S, Kawahara TL, Zhang JY, Segal E and Chang HA. Motif map reveals enforcement of aging by continual
NF-kB activity. Genes and Dev 21: 3244-3257, 2007.
10. Giunta, C., Elçioglu, N., Albrecht, B., Eich, G., Chambaz, C., Janecke, A.R., Yeowell, H.N., Eyre, D., Kraenzlin, B., and Steinmann, B. Spondylo-Cheiral Form of the Ehlers-Danlos Syndrome - A Novel
Autosomal Recessive Entity Caused by Mutations in the Zinc Transporter Gene SLC39A13.
Am. J. Hum. Genet. 82 (6): 1290-1305, 2008 |
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